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Symptoms of overdose
It is especially important to check with your doctor before combining Zyban with the following:
- Alcohol
- Amantadine (Symmetrel)
- Antidepressants such as Norpramin, Pamelor, Pa
xil, Prozac, Tofranil, and Zoloft
- Beta blockers (heart and blood pressure medications) such as Inderal, Lopressor, and Tenormin
- Carbamazepine (Tegretol)
- Cimetidine (Tagamet)
- Cyclophosphamide (Cytoxan)
- Heart-stabilizing drugs such as Rythmol and Tambocor
- Levodopa (Dopar, Larodopa, Sinemet)
- Major tranquilizers such as Haldol, Risperdal and Thorazine <
br> - MAO inhibitors such as the antidepressants Nardil and Parnate
- Orphenadrine (Norflex)
- Phenobarbital
- Phenytoin (Dilantin)
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How should this medicine be used?
Zyban comes as a tablet to take by mouth. It is usually taken one to three times a day and may be taken with or without food. Do not crush, chew, or divide Wellbutrin SR or Zyban tablets. Follow the d
irections on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Zyban exactly as directed.
Continue to take Zyban even if you
feel well. Do not stop taking Zyban without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease your dose gradually. This drug
must be taken regularly for a few weeks before its full effect is felt.
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What special precautions should I follow?
Older adults¡XThis medicine has been tested in a limited number of patients 60 years of age and older and has not been shown to cause different side effects or problems in older people than it does in
younger adults.
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What side effects can this medication cause?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Zyban.
<
br> The most common side effects are:
Dry mouth and sleeplessness
These are generally mild and usually disappear after a few weeks. If you have difficulty sleeping, avoid taking Zyban close t
o bedtime and ask your doctor about reducing your dosage.
More common side effects may include:
Abdominal pain, abnormal dreams, anxiety, constipation, diarrhea, disturbed concentration
, dizziness, joint pain, increased cough, itching, nasal inflammation, nausea, nervousness, rash, sore throat
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Cautions
Your doctor should check your progress at regular visits, especially during the first few months of treatment with this medicine. The amount of Zyban you take may have to be changed often to meet the
needs of your condition and to help avoid unwanted effects.
Do not take Zyban within 14 days of taking an MAO inhibitor.
Zyban is sold under different brand names for different uses.
If you are already taking medicine for mental depression or to help you stop smoking, discuss this with your health care professional before taking Zyban. It is very important that you receive only o
ne prescription for Zyban at a time.
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Significant Interactions:
When you are taking Zyban, it is especially important that your health care professional know if you are taking any of the following:
- Tricyclic antidepressants (amitriptyline [e.g., Elavil
], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g.,
Vivactil], trimipramine [e.g., Surmontil]) or
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- Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegi
line [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X Do not take Zyban while you are taking or within 14 days of taking an MAO inhibitor
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